Changing paradigms from a historical DSM-III and DSM-IV view toward an evidence-based definition of premature ejaculation. 1989 15:130-4.) and two more types of PE have been suggested as naturel variable PE and premature-like ejaculatory dysfunction by Waldinger and Schweitzer ( 3 3. Premature ejaculation: clinical subgroups and etiology. Firstly, Godpodinoff defined both types as lifelong and acquired PE ( 2 2.
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The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking. Porst H, Montorsi F, Rosen RC, Gaynor L, Grupe S, Alexander J. Premature ejaculation (PE) is defined as a lack of control on ejaculation and it is the most common sexual dysfunction that may affect 20%– 30% of men ( 1 1. Premature Ejaculation Vitamin D Likelihood Functions Perhaps supplementation of vitamin D in men with acquired PE will ameliorate the sexual health of these patients.
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The result of our study showed that the role of serum vitamin D levels should be investigate in the etiology of acquired PE. This study demonstrates that lower vitamin D levels are associated with the acquired PE.
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The best cut-off value was 16 ng/mL with a sensitivity of 60.9%, specificity of 83.5%, PPV of 70.9%, and NPV of 76.4% to indicate acquired PE. In the logistic regression analysis, 25 (OH) D was found to be an independent risk factor for acquired PE, with estimated odds ratios (95% CI) of 0.639 (0.460-0.887, p = 0.007) and the area under curve of the ROC curve of 25 (OH) D diagnosing acquired PE was 0.770 (95% CI: 0.695 to 0.844, p < 0.001). Results:Ĭompared to men without PE, the patients with acquired PE had significantly lower 25 (OH) D levels (12.0 ± 4.5 ng/mL vs.
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Vitamin D levels were evaluated in all participants using high performance liquid chromatography method included in the study. Premature ejaculation diagnostic tool questionnaires were used to assessment of PE and all participants were instructed to record intravaginal ejaculatory latency time. All patients were considered to have acquired PE if they fulfilled the criteria of the second Ad Hoc International Society for Sexual Medicine Committee. Materials and Methods:Ī total of 97 patients with acquired PE and 64 healthy men as a control group selected from volunteers without PE attending our Andrology Outpatient Clinic between November 2016 and April 2017 were included the study. To investigate the relationship between 25-hydroxyvitamin D (25 (OH) D) levels and acquired premature ejaculation (PE).
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Correspondence address: Lütfi Canat, MD, Department of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey, Telephone: + 90 505 530-1894 E-mail: of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Recep Burak Degirmentepeĭepartment of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Hasan Anil Atalayĭepartment of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Suleyman Sami Çakirĭepartment of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Ilter Alkanĭepartment of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Mehmet Gokhan Çulhaĭepartment of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Sait Ozbirĭepartment of Urology, Okmeydani Training and Research Hospital, Istanbul, Turkey Masum Canatĭepartment of Endocrinology and Metabolism, Şişli Etfal Training and Research Hospital, Istanbul, Turkey About the authors